What is GLP-1? GLP-1 (Glucagon-Like Peptide-1) is a naturally occurring hormone released after meals. It helps regulate blood sugar levels, slows stomach emptying, and signals the brain that you are full. Modern GLP-1 medications mimic these natural effects, making them valuable tools for weight management and metabolic health. Newer medications such as Tirzepatide also activate GIP receptors, offering enhanced weight-loss and glucose-control benefits in many clinical studies